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M on March 23rd, 2012

Freckles and Ryley are growing up so fast, not quite full grown yet, but they have almost lost their puppy look.  They have definitely hit that teenage boy stage but show flashes of the brilliant dogs they are growing into.  Freckles is the softer of the two, whereas Ryley is hard headed and independant but […]

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M on December 11th, 2009

Zeke and Bolt are getting very brave and adventurous now, and both take pleasure in being very cheeky! We’ve introduced them to raw meaty bones which they attack like little wolves, and they thoroughly enjoy the raw mince mixed with their puppy kibble. The chest freezer arrived Wednesday (complete with *major* dent, but thats another […]

Continue reading about Pups and whistles

Serenade with satirical whistle

Older men with diabetes mellitus, but also severely overweight men, may develop secondary hypogonadism. "The core symptom of low testosterone levels is usually decreased libido," Dr. Cornelia Jaursch-Hancke from the German Clinic for Diagnostics, Sydney, at the conference in Melbourne. Various additional symptoms such as osteoporosis, anemia, erectile dysfunction, decreasing muscle strength and mass, but also diminishing vitality and depression can be added. In secondary hypogonadism the function of the hypothalamus or pituitary is impaired so that the Leydig cells of the testicle no longer form testosterone or no testosterone due to lack of stimulation. Typically, the gonadotropins LH and FSH in the serum are still normal to low. This also applies to patients with type 2 diabetes, of which about 25 to 50 percent are affected, the endocrinologist reported. An increasing problem is also MOSH, the "male obesity associated secondary hypogonadism". As a cause, she described the visceral fetal cells, which are highly active endocrinically and produce mediators, which promote, inter alia, insulin resistance, inflammatory processes and dyslipidemia and stimulate estradiol production. In sum, the hypothalamic-pituitary axis is inhibited. Continue reading...

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